PREY

RABEP1

RAB5EP, RABPT5
rabaptin, RAB GTPase binding effector protein 1
GO Process (1)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER.

Valsdottir R, Hashimoto H, Ashman K, Koda T, Storrie B, Nilsson T

The role of rab33b, a Golgi-specific rab protein, was investigated. Microinjection of rab33b mutants stabilised in the GTP-specific state resulted in a marked inhibition of anterograde transport within the Golgi and in the recycling of glycosyltransferases from the Golgi to the ER, respectively. A GST-rab33b fusion protein stabilised in its GTP form was found to interact by Western blotting or ... [more]

FEBS Lett. Nov. 16, 2001; 508(2);201-9 [Pubmed: 11718716]

Throughput

  • Low Throughput

Curated By

  • BioGRID