Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Myo-inositol monophosphatase is an activated target of calbindin D28k.

Berggard T, Szczepankiewicz O, Thulin E, Linse S

Calbindin D(28k) (calbindin) is a member of the calmodulin superfamily of Ca(2+)-binding proteins. An intracellular target of calbindin was discovered using bacteriophage display. Human recombinant calbindin was immobilized on magnetic beads and used in affinity purification of phage-displayed peptides from a random 12-mer peptide library. One sequence, SYSSIAKYPSHS, was strongly selected both in the presence of Mg(2+) and in the ... [more]

J. Biol. Chem. Nov. 01, 2002; 277(44);41954-9 [Pubmed: 12176979]

Throughput

  • Low Throughput

Curated By

  • BioGRID