BAIT
TRIP6
OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1, tcag7.1300
thyroid hormone receptor interactor 6
GO Process (3)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TPM4
HEL-S-108
tropomyosin 4
GO Process (4)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.
Integrin binding to extracellular matrix proteins induces formation of signaling complexes at focal adhesions. Zyxin co-localizes with integrins at sites of cell-substratum adhesion and is postulated to serve as a docking site for the assembly of multimeric protein complexes involved in regulating cell motility. Recently, we identified a new member of the zyxin family called TRIP6. TRIP6 is localized at ... [more]
J. Biol. Chem. Mar. 15, 2002; 277(11);9580-9 [Pubmed: 11782456]
Throughput
- Low Throughput
Curated By
- BioGRID