RPO21
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CMD1
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [IMP]
- cell budding [IMP]
- cytoskeleton organization [IMP]
- karyogamy involved in conjugation with cellular fusion [IGI, IMP]
- microautophagy [IMP]
- phosphatidylinositol biosynthetic process [IGI, IMP]
- receptor-mediated endocytosis [IMP]
- spindle pole body organization [IMP]
- transcription factor import into nucleus [IMP]
- vacuole fusion, non-autophagic [IDA, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The deubiquitylase Ubp15 couples transcription to mRNA export.
Nuclear export of messenger RNAs (mRNAs) is intimately coupled to their synthesis. pre-mRNAs assemble into dynamic ribonucleoparticles as they are being transcribed, processed, and exported. The role of ubiquitylation in this process is increasingly recognized but, while a few E3 ligases have been shown to regulate nuclear export, evidence for deubiquitylases is currently lacking. Here we identified deubiquitylase Ubp15 as ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CMD1 RPO21 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2928 | BioGRID | 1920804 |
Curated By
- BioGRID