BAIT

TRIM37

MUL, POB1, TEF3
tripartite motif containing 37
UPS Project
Homo sapiens
PREY

PABPC4

APP-1, APP1, PABP4, iPABP
poly(A) binding protein, cytoplasmic 4 (inducible form)
GO Process (4)
GO Function (5)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT-GSK-3?-?-Catenin Signaling Pathway.

Chen S, He Z, Zhu C, Liu Y, Li L, Deng L, Wang J, Yu C, Sun C

The tripartite motif-containing family member TRIM37 is involved in a number of important biological and pathological processes, and it has recently been shown to be an essential regulator of protein ubiquitination and a contributor to tumorigenesis. We previously showed that TRIM37 is overexpressed in and promotes the proliferation and invasion of pancreatic cancer (PC).Sphere formation, flow cytometric, qRT-PCR, western blot, ... [more]

Front Oncol Nov. 17, 2020; 10();554787 [Pubmed: 33194618]

Throughput

  • High Throughput

Additional Notes

  • High confidence interaction

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PABPC4 TRIM37
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

High-BioGRID
-
TRIM37 PABPC4
Protein-RNA
Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

High-BioGRID
-

Curated By

  • BioGRID