BAIT
USP2
UBP41, USP9
ubiquitin specific peptidase 2
GO Process (10)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- circadian behavior [ISS]
- circadian regulation of gene expression [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- locomotor rhythm [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of mitotic cell cycle [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IDA]
- protein stabilization [IDA, IMP]
- regulation of proteasomal protein catabolic process [IBA]
Gene Ontology Molecular Function
Homo sapiens
PREY
AHNAK
AHNAKRS
AHNAK nucleoprotein
GO Process (3)
GO Function (4)
GO Component (15)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Ubiquitin-specific protease 2a promotes hepatocellular carcinoma progression via deubiquitination and stabilization of RAB1A.
Deubiquitination, the inverse process of ubiquitination, is catalyzed by deubiquitinases (DUBs) that remove ubiquitin from target proteins and subsequently prevent their degradation by proteasomes. Previously, deubiquitination has been found to be involved in hepatocellular carcinoma (HCC) progression. As yet, however, little is known about the exact role of deubiquitination in the development and/or progression of this type of cancer.HCC tissues ... [more]
Cell Oncol (Dordr) Apr. 01, 2021; 44(2);329-343 [Pubmed: 33074477]
Throughput
- High Throughput
Curated By
- BioGRID