BAIT

TLE4

BCE-1, BCE1, E(spI), ESG, ESG4, GRG4, Grg-4, RP11-79D8.3
transducin-like enhancer of split 4
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

FMR1

FMRP, FRAXA, POF, POF1
fragile X mental retardation 1
Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X

Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance significantly limits its therapeutic efficacy, and the mechanisms underlying resistance have not been fully clarified. Here we report that a circular RNA, circRNA-SORE (a circular RNA upregulated in sorafenib-resistant HCC cells), plays a significant role in sorafenib resistance in HCC. We found that circRNA-SORE is upregulated ... [more]

Signal Transduct Target Ther Dec. 26, 2019; 5(1);298 [Pubmed: 33361760]

Throughput

  • Low Throughput

Additional Notes

  • These interactions refer to CircRNA-SORE, derived from the 7th and 8th exons of the TLE4 gene and generated into a circular form by back-splicing.

Curated By

  • BioGRID