BAIT
TRIM9
RNF91, SPRING
tripartite motif containing 9
GO Process (1)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PCM1
2600002H09Rik, 9430077F19Rik, C030044G17Rik
pericentriolar material 1
GO Process (11)
GO Function (1)
GO Component (10)
Gene Ontology Biological Process
- centrosome organization [ISO]
- cilium assembly [ISO]
- cytoplasmic microtubule organization [ISO]
- interkinetic nuclear migration [IMP]
- intraciliary transport involved in cilium morphogenesis [ISO]
- microtubule anchoring [IMP]
- microtubule anchoring at centrosome [IMP]
- negative regulation of neurogenesis [IMP]
- neuronal stem cell maintenance [IMP]
- positive regulation of intracellular protein transport [ISO]
- protein localization to centrosome [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits, particularly in spatial learning and memory. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome ... [more]
Mol Biol Cell Dec. 15, 2020; 32(4);314-330 [Pubmed: 33378226]
Throughput
- Low Throughput
Additional Notes
- species of bait is unclear
Curated By
- BioGRID