BAIT
TRIM9
RNF91, SPRING
tripartite motif containing 9
GO Process (1)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
LIMD1
AW822033, D9Ertd192e
LIM domains containing 1
GO Process (14)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- cell migration [ISO]
- cytoplasmic mRNA processing body assembly [ISO]
- cytoskeleton organization [ISO]
- gene silencing by miRNA [ISO]
- negative regulation of canonical Wnt signaling pathway [IMP]
- negative regulation of hippo signaling [ISO]
- negative regulation of nucleic acid-templated transcription [IDA]
- negative regulation of osteoblast differentiation [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- osteoblast development [IMP]
- phosphorylation [ISO]
- positive regulation of gene silencing by miRNA [ISO]
- regulation of cell shape [ISO]
- response to hypoxia [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits, particularly in spatial learning and memory. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome ... [more]
Mol Biol Cell Dec. 15, 2020; 32(4);314-330 [Pubmed: 33378226]
Throughput
- Low Throughput
Additional Notes
- species of bait is unclear
Curated By
- BioGRID