BAIT

TRIM9

RNF91, SPRING
tripartite motif containing 9
UPS Project
GO Process (1)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

AGO2

1110029L17Rik, 2310051F07Rik, AI225898, AL022874, AW546247, ENSMUSG00000072493, Eif2c2, Gerp95, Gm10365, mKIAA4215
argonaute RISC catalytic subunit 2
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

Menon S, Goldfarb D, Ho CT, Cloer EW, Boyer NP, Hardie C, Bock AJ, Johnson EC, Anil J, Major MB, Gupton SL

TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits, particularly in spatial learning and memory. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome ... [more]

Mol Biol Cell Dec. 15, 2020; 32(4);314-330 [Pubmed: 33378226]

Throughput

  • Low Throughput

Additional Notes

  • species of bait is unclear

Curated By

  • BioGRID