BAIT
TRIM9
RNF91, SPRING
tripartite motif containing 9
GO Process (1)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PRPS1
2310010D17Rik, C76571, C76678, PRS-I, Prps-1, RP23-137E3.3
phosphoribosyl pyrophosphate synthetase 1
GO Process (9)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- 5-phosphoribose 1-diphosphate biosynthetic process [ISO]
- AMP biosynthetic process [ISO]
- hypoxanthine biosynthetic process [ISO]
- nervous system development [ISO]
- nucleotide biosynthetic process [ISO]
- purine nucleobase metabolic process [ISO]
- purine nucleotide biosynthetic process [ISO]
- ribose phosphate metabolic process [ISO]
- urate biosynthetic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits, particularly in spatial learning and memory. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome ... [more]
Mol Biol Cell Dec. 15, 2020; 32(4);314-330 [Pubmed: 33378226]
Throughput
- Low Throughput
Additional Notes
- species of bait is unclear
Curated By
- BioGRID