BAIT
TRIM67
TNL
tripartite motif containing 67
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
HOOK3
5830454D03Rik, AI317159, E330005F07Rik
hook homolog 3 (Drosophila)
GO Process (11)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- Golgi localization [ISO]
- cytoplasmic microtubule organization [ISO]
- early endosome to late endosome transport [ISO]
- endosome organization [ISO]
- endosome to lysosome transport [ISO]
- interkinetic nuclear migration [IMP]
- lysosome organization [ISO]
- microtubule anchoring at centrosome [IMP]
- negative regulation of neurogenesis [IMP]
- neuronal stem cell maintenance [IMP]
- protein localization to centrosome [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.
TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits, particularly in spatial learning and memory. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome ... [more]
Mol Biol Cell Dec. 15, 2020; 32(4);314-330 [Pubmed: 33378226]
Throughput
- Low Throughput
Additional Notes
- species of bait is unclear
Curated By
- BioGRID