BAIT
CDY1
CDY, CDY1A
chromodomain protein, Y-linked, 1
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
LIG1
ligase I, DNA, ATP-dependent
GO Process (16)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- DNA metabolic process [TAS]
- DNA repair [TAS]
- DNA strand elongation involved in DNA replication [TAS]
- V(D)J recombination [IDA]
- anatomical structure morphogenesis [TAS]
- base-excision repair [TAS]
- double-strand break repair [TAS]
- double-strand break repair via homologous recombination [TAS]
- lagging strand elongation [IBA]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [IBA, TAS]
- nucleotide-excision repair, DNA gap filling [TAS]
- telomere maintenance [TAS]
- telomere maintenance via recombination [TAS]
- telomere maintenance via semi-conservative replication [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
The chromatin-binding E3 ubiquitin ligase ubiquitin-like with PHD and RING finger domains 1 (UHRF1) contributes to the maintenance of aberrant DNA methylation patterning in cancer cells through multivalent histone and DNA recognition. The tandem Tudor domain (TTD) of UHRF1 is well-characterized as a reader of lysine 9 di- and tri-methylation on histone H3 (H3K9me2/me3) and, more recently, lysine 126 di- ... [more]
Epigenetics Chromatin Dec. 23, 2019; 13(1);44 [Pubmed: 33097091]
Throughput
- Low Throughput
Curated By
- BioGRID