BAIT
MIER1
ER1, MI-ER1, RP5-944N15.1
mesoderm induction early response 1, transcriptional regulator
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LIG1
ligase I, DNA, ATP-dependent
GO Process (16)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- DNA metabolic process [TAS]
- DNA repair [TAS]
- DNA strand elongation involved in DNA replication [TAS]
- V(D)J recombination [IDA]
- anatomical structure morphogenesis [TAS]
- base-excision repair [TAS]
- double-strand break repair [TAS]
- double-strand break repair via homologous recombination [TAS]
- lagging strand elongation [IBA]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [IBA, TAS]
- nucleotide-excision repair, DNA gap filling [TAS]
- telomere maintenance [TAS]
- telomere maintenance via recombination [TAS]
- telomere maintenance via semi-conservative replication [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.
The chromatin-binding E3 ubiquitin ligase ubiquitin-like with PHD and RING finger domains 1 (UHRF1) contributes to the maintenance of aberrant DNA methylation patterning in cancer cells through multivalent histone and DNA recognition. The tandem Tudor domain (TTD) of UHRF1 is well-characterized as a reader of lysine 9 di- and tri-methylation on histone H3 (H3K9me2/me3) and, more recently, lysine 126 di- ... [more]
Epigenetics Chromatin Dec. 23, 2019; 13(1);44 [Pubmed: 33097091]
Throughput
- Low Throughput
Curated By
- BioGRID