BAIT
SYVN1
1200010C09Rik, AW211966, C85322, D530017H19Rik, Hrd1
synovial apoptosis inhibitor 1, synoviolin
GO Process (6)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- ER-associated ubiquitin-dependent protein catabolic process [ISO]
- in utero embryonic development [IMP]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [IMP]
- protein N-linked glycosylation via asparagine [ISO]
- protein ubiquitination [ISO]
- response to unfolded protein [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MYH9
Fltn, Myhn-1, Myhn1, NMHCIIA, NMMHC-A, NMMHC-IIA, TU72.6, AL583886.1
myosin, heavy polypeptide 9, non-muscle
GO Process (22)
GO Function (11)
GO Component (26)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton reorganization [ISO]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- angiogenesis [ISO]
- blood vessel endothelial cell migration [ISO]
- cell adhesion [IMP]
- cell morphogenesis involved in differentiation [IMP]
- cellular component movement [IMP]
- cytokinesis [ISO]
- establishment of T cell polarity [IMP]
- establishment of meiotic spindle localization [IDA]
- in utero embryonic development [IMP]
- meiotic spindle organization [IDA]
- membrane protein ectodomain proteolysis [ISO]
- myoblast fusion [IMP]
- platelet aggregation [ISO]
- platelet formation [ISO]
- protein transport [ISO]
- regulation of cell shape [IMP, ISO]
- single organismal cell-cell adhesion [IMP]
- uropod organization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- COP9 signalosome [ISO]
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- actomyosin contractile ring [ISO]
- cell cortex [IDA]
- cell leading edge [ISO]
- cell-cell adherens junction [IDA]
- cleavage furrow [ISO]
- cortical cytoskeleton [IDA]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- immunological synapse [IDA, ISO]
- integrin complex [ISO]
- membrane [ISO]
- myosin II complex [IDA, ISO]
- myosin II filament [ISO]
- myosin complex [IDA]
- neuromuscular junction [IDA]
- nucleus [ISO]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- ruffle [ISO]
- spindle [IDA]
- stress fiber [IDA, ISO]
- uropod [IDA, ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.
The functions of Acly in regulating nonalcoholic fatty liver disease (NAFLD) have been identified; however, the dynamic control of Acly expression under the pathological state of metabolic disorders has not been fully elucidated. Previous studies reported an ubiquitin-proteasome-mediated degradation of Acly, but the mechanism is still largely unknown.Co-IP-based mass spectrum (MS/MS) assays were performed in HepG2 and Hepa1-6 hepatocytes and ... [more]
Metabolism Dec. 01, 2020; 114();154349 [Pubmed: 32888949]
Throughput
- High Throughput
Curated By
- BioGRID