BAIT
SYVN1
1200010C09Rik, AW211966, C85322, D530017H19Rik, Hrd1
synovial apoptosis inhibitor 1, synoviolin
GO Process (6)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- ER-associated ubiquitin-dependent protein catabolic process [ISO]
- in utero embryonic development [IMP]
- negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [IMP]
- protein N-linked glycosylation via asparagine [ISO]
- protein ubiquitination [ISO]
- response to unfolded protein [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PACSIN2
AI197433
protein kinase C and casein kinase substrate in neurons 2
GO Process (8)
GO Function (6)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- caveola [IDA, ISO]
- cell-cell junction [IDA]
- cytoplasm [IDA, ISO]
- cytosol [IDA]
- endosome [IBA]
- extracellular vesicular exosome [ISO]
- extrinsic component of membrane [IDA]
- focal adhesion [ISO]
- intracellular membrane-bounded organelle [ISO]
- membrane-bounded vesicle [IBA]
- nucleoplasm [ISO]
- recycling endosome membrane [ISO]
- trans-Golgi network [IDA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.
The functions of Acly in regulating nonalcoholic fatty liver disease (NAFLD) have been identified; however, the dynamic control of Acly expression under the pathological state of metabolic disorders has not been fully elucidated. Previous studies reported an ubiquitin-proteasome-mediated degradation of Acly, but the mechanism is still largely unknown.Co-IP-based mass spectrum (MS/MS) assays were performed in HepG2 and Hepa1-6 hepatocytes and ... [more]
Metabolism Dec. 01, 2020; 114();154349 [Pubmed: 32888949]
Throughput
- High Throughput
Curated By
- BioGRID