BAIT

HMGB1

HMG1, HMG3, SBP-1, RP11-550P23.1
high mobility group box 1
GO Process (22)
GO Function (13)
GO Component (7)
Homo sapiens
PREY

RASAL2

NGAP, RP4-593C16.1
RAS protein activator like 2
GO Process (2)
GO Function (2)
GO Component (2)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications.

Barreiro-Alonso A, Camara-Quilez M, Salamini-Montemurri M, Lamas-Maceiras M, Vizoso-Vazquez A, Rodriguez-Belmonte E, Quindos-Varela M, Martinez-Iglesias O, Figueroa A, Cerdan ME

High mobility group box B (HMGB) proteins are pivotal in the development of cancer. Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement of HMGB proteins and their interactome in PCa is an unexplored field of considerable interest. We describe herein the results of the first HMGB1/HMGB2 interactome approach to PCa. Libraries constructed from the PCa ... [more]

Cancers (Basel) Nov. 05, 2019; 11(11); [Pubmed: 31694235]

Throughput

  • High Throughput

Curated By

  • BioGRID