BAIT
FXR2
FMR1L2, FXR2P
fragile X mental retardation, autosomal homolog 2
GO Process (1)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
CBS
HIP4
cystathionine-beta-synthase
GO Process (10)
GO Function (9)
GO Component (4)
Gene Ontology Biological Process
- L-cysteine catabolic process [IDA]
- L-serine catabolic process [IDA]
- L-serine metabolic process [IDA]
- cellular nitrogen compound metabolic process [TAS]
- homocysteine catabolic process [IDA]
- homocysteine metabolic process [IDA]
- hydrogen sulfide biosynthetic process [IDA, ISS]
- small molecule metabolic process [TAS]
- sulfur amino acid metabolic process [TAS]
- transsulfuration [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interactome reveals converging molecular pathways among autism disorders.
To uncover shared pathogenic mechanisms among the highly heterogeneous autism spectrum disorders (ASDs), we developed a protein interaction network that identified hundreds of new interactions among proteins encoded by ASD-associated genes. We discovered unexpectedly high connectivity between SHANK and TSC1, previously implicated in syndromic autism, suggesting that common molecular pathways underlie autistic phenotypes in distinct syndromes. ASD patients were more ... [more]
Sci Transl Med Jun. 08, 2011; 3(86);86ra49 [Pubmed: 21653829]
Throughput
- High Throughput
Related interactions
Curated By
- BioGRID