BAIT
HOXA1
BSAS, HOX1, HOX1F
homeobox A1
GO Process (16)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
- abducens nerve formation [IMP]
- anatomical structure morphogenesis [IMP]
- artery development [IMP]
- artery morphogenesis [IMP]
- cochlea development [IMP]
- cochlea morphogenesis [IMP]
- cognition [IDA]
- embryonic neurocranium morphogenesis [IMP]
- inner ear development [IMP]
- multicellular organismal development [TAS]
- neuromuscular process [IDA]
- optokinetic behavior [IDA]
- outer ear morphogenesis [IDA]
- regulation of behavior [IDA]
- semicircular canal formation [IMP]
- sensory perception of sound [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
MEGF8
C19orf49, CRPT2, EGFL4, SBP1
multiple EGF-like-domains 8
GO Process (15)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- BMP signaling pathway [ISS]
- cell migration involved in gastrulation [IMP]
- craniofacial suture morphogenesis [IMP]
- determination of digestive tract left/right asymmetry [ISS]
- determination of heart left/right asymmetry [IMP]
- embryonic heart tube left/right pattern formation [ISS]
- embryonic heart tube morphogenesis [ISS]
- embryonic limb morphogenesis [ISS]
- embryonic skeletal system morphogenesis [ISS]
- epiboly involved in gastrulation with mouth forming second [IMP]
- fasciculation of sensory neuron axon [ISS]
- left/right pattern formation [IMP]
- limb morphogenesis [IMP]
- positive regulation of axon extension involved in axon guidance [ISS]
- regulation of gene expression [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interactome reveals converging molecular pathways among autism disorders.
To uncover shared pathogenic mechanisms among the highly heterogeneous autism spectrum disorders (ASDs), we developed a protein interaction network that identified hundreds of new interactions among proteins encoded by ASD-associated genes. We discovered unexpectedly high connectivity between SHANK and TSC1, previously implicated in syndromic autism, suggesting that common molecular pathways underlie autistic phenotypes in distinct syndromes. ASD patients were more ... [more]
Sci Transl Med Jun. 08, 2011; 3(86);86ra49 [Pubmed: 21653829]
Throughput
- High Throughput
Curated By
- BioGRID