BAIT
PAX5
BSAP, EBB-1, KLP, Pax-5, RP23-397E2.1
paired box 5
GO Process (9)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of histone H3-K9 methylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [TAS]
- organ morphogenesis [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- positive regulation of transcription, DNA-templated [TAS]
- regulation of transcription, DNA-templated [IDA]
- skeletal muscle cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA, IMP]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA, IMP]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
Mus musculus
PREY
KPNA2
IPOA1, QIP2, RCH1, SRP1alpha
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
GO Process (4)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence.
BSAP (Pax5) is an essential transcription factor for early B cell and central nervous system development. In later B cell development, BSAP has been implicated in the regulation of 3' Ig enhancers and a number of B cell-specific genes. Previous studies have suggested a role for BSAP-interacting proteins in the regulation of the function of BSAP. Using the yeast two-hybrid ... [more]
J. Biol. Chem. Jun. 02, 2000; 275(22);16752-7 [Pubmed: 10748034]
Throughput
- Low Throughput
Curated By
- BioGRID