BAIT
TSHR
CHNG1, LGR3, hTSHR-I
thyroid stimulating hormone receptor
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FLNB
ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP
filamin B, beta
GO Process (4)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulins.
Human actin binding protein (ABP) links specific membrane glycoproteins to cytoskeletal actin microfilaments. In human platelets and leukocytes, ABP directly links, respectively, the membrane glycoproteins GPIb and the high-affinity Fc receptor for IgG (Fc gamma IR) to cytoskeletal actin microfilaments. Similar interaction between the thyrotropin (TSH) receptor and ABP in endocrine cells might explain the rapid and profound disruption of ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jul. 01, 1993; 90(13);5994-8 [Pubmed: 8327473]
Throughput
- Low Throughput
Curated By
- BioGRID