BAIT
NUDCD2
NudC domain containing 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BASP1
CAP-23, CAP23, NAP-22, NAP22
brain abundant, membrane attached signal protein 1
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- diaphragm development [ISS]
- glomerular visceral epithelial cell differentiation [ISS]
- gonad development [ISS]
- mesenchymal to epithelial transition [ISS]
- metanephric mesenchyme development [ISS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of heart growth [ISS]
- positive regulation of metanephric ureteric bud development [ISS]
- substantia nigra development [IEP]
- thorax and anterior abdomen determination [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.
Cell migration plays pivotal roles in many biological processes; however, its underlying mechanism remains unclear. Here, we find that NudC-like protein 2 (NudCL2), a cochaperone of heat shock protein 90 (Hsp90), modulates cell migration by stabilizing both myosin-9 and lissencephaly protein 1 (LIS1). Either knockdown or knockout of NudCL2 significantly increases single-cell migration, but has no significant effect on collective ... [more]
Cell Death Dis Dec. 14, 2019; 11(7);534 [Pubmed: 32665550]
Throughput
- High Throughput
Curated By
- BioGRID