SLC6A3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TGFB1I1
Gene Ontology Biological Process
- cell fate commitment [IGI]
- epithelial cell differentiation [IGI]
- morphogenesis of embryonic epithelium [IMP]
- negative regulation of fat cell differentiation [IGI]
- negative regulation of transforming growth factor beta receptor signaling pathway [ISO]
- positive regulation of epithelial to mesenchymal transition [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- positive regulation of transforming growth factor beta receptor signaling pathway [ISO]
- response to heat [ISO]
- ubiquitin-dependent SMAD protein catabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter.
The Na+/Cl--dependent dopamine transporter (DAT) is critical in terminating dopaminergic transmission by removing the transmitter away from the synapse. Several lines of evidence suggest that transporter-interacting proteins may play a role in DAT function and regulation. In this report, using the yeast two-hybrid system, we have identified a novel interaction between DAT and the multiple Lin-11, Isl-1, and Mec-3 (LIM) ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID