BAIT
NUDCD2
NudC domain containing 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PABPN1
OPMD, PAB2, PABII, PABP-2, PABP2
poly(A) binding protein, nuclear 1
GO Process (13)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- RNA processing [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- mRNA 3'-end processing [TAS]
- mRNA splicing, via spliceosome [TAS]
- modification by virus of host mRNA processing [TAS]
- modulation by virus of host morphology or physiology [TAS]
- modulation by virus of host process [TAS]
- muscle contraction [TAS]
- poly(A)+ mRNA export from nucleus [IMP]
- termination of RNA polymerase II transcription [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral life cycle [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.
Cell migration plays pivotal roles in many biological processes; however, its underlying mechanism remains unclear. Here, we find that NudC-like protein 2 (NudCL2), a cochaperone of heat shock protein 90 (Hsp90), modulates cell migration by stabilizing both myosin-9 and lissencephaly protein 1 (LIS1). Either knockdown or knockout of NudCL2 significantly increases single-cell migration, but has no significant effect on collective ... [more]
Cell Death Dis Dec. 14, 2019; 11(7);534 [Pubmed: 32665550]
Throughput
- High Throughput
Curated By
- BioGRID