BAIT
NAA40
NAT11, PATT1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
SRGAP2
ARHGAP34, FNBP2, SRGAP2A, SRGAP3, RP11-312O7.2
SLIT-ROBO Rho GTPase activating protein 2
GO Process (14)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- actin filament severing [IDA]
- axon guidance [TAS]
- cell proliferation [IMP]
- dendritic spine development [IDA]
- extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration [ISS]
- filopodium assembly [IDA]
- lamellipodium assembly involved in ameboidal cell migration [IMP]
- negative regulation of cell death [IMP]
- negative regulation of neuron migration [IDA]
- neuron projection morphogenesis [ISS]
- positive regulation of Rac GTPase activity [IDA, IMP]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- substrate adhesion-dependent cell spreading [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.
The evolutionary conserved N-alpha acetyltransferase Naa40p is among the most selective N-terminal acetyltransferases (NATs) identified to date. Here we identified a conserved N-terminally truncated Naa40p proteoform named Naa40p25 or short Naa40p (Naa40S). Intriguingly, although upon ectopic expression in yeast, both Naa40p proteoforms were capable of restoring N-terminal acetylation of the characterized yeast histone H2A Naa40p substrate, the Naa40p histone H4 ... [more]
Int J Mol Sci Apr. 01, 2021; 22(7); [Pubmed: 33916271]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID