BAIT
F10
FX, FXA, RP11-98F14.9
coagulation factor X
GO Process (9)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- blood coagulation [IC, TAS]
- blood coagulation, extrinsic pathway [TAS]
- blood coagulation, intrinsic pathway [TAS]
- cellular protein metabolic process [TAS]
- peptidyl-glutamic acid carboxylation [TAS]
- positive regulation of cell migration [TAS]
- positive regulation of protein kinase B signaling [IDA]
- post-translational protein modification [TAS]
- proteolysis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PLAT
T-PA, TPA
plasminogen activator, tissue
GO Process (5)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Binding of plasminogen and tissue plasminogen activator to plasmin-modulated factor X and factor Xa.
Previous work in our laboratory has suggested that the fibrinolytic enzyme plasmin (Pn) inactivates coagulation factors X (FX) and Xa (FXa) in the presence of Ca(2+) and anionic phospholipid (aPL), producing fragments which bind plasminogen (Pg) and accelerate tissue plasminogen activator (t-PA). Our goals here were to determine if the Pn-mediated fragments of FX or FXa remain associated, whether they ... [more]
Biochemistry May. 29, 2001; 40(21);6293-302 [Pubmed: 11371191]
Throughput
- Low Throughput
Curated By
- BioGRID