BAIT
GRSF1
G-rich RNA sequence binding factor 1
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DACT1
DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
dishevelled-binding antagonist of beta-catenin 1
GO Process (12)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- embryonic hindgut morphogenesis [ISS]
- negative regulation of G1/S transition of mitotic cell cycle [IDA]
- negative regulation of JNK cascade [IDA]
- negative regulation of Wnt signaling pathway [IDA, IGI, IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of Wnt signaling pathway [IDA]
- positive regulation of catenin import into nucleus [IMP]
- positive regulation of protein catabolic process [IDA]
- regulation of Wnt signaling pathway, planar cell polarity pathway [ISS]
- regulation of catenin import into nucleus [IMP]
- regulation of nodal signaling pathway [IDA]
- regulation of protein stability [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.
The guanine-rich RNA sequence binding factor 1 (GRSF1) is an RNA-binding protein of the hnRNP H/F family, which has been implicated in erythropoiesis, regulation of the redox homeostasis, embryonic brain development, mitochondrial function and cellular senescence. The molecular basis for GRSF1-RNA interaction has extensively been studied in the past but for the time being GRSF1 binding proteins have not been ... [more]
Biochim Biophys Acta Gen Subj Dec. 01, 2019; 1864(11);129678 [Pubmed: 32645484]
Throughput
- Low Throughput
Curated By
- BioGRID