BAIT
MALAT1
HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO2853, mascRNA, PRO1073
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
LIG3
LIG2
ligase III, DNA, ATP-dependent
GO Process (7)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- chromosome [IBA]
- mitochondrion [IBA, IDA]
- nucleoplasm [IDA, TAS]
- nucleus [IDA]
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Targeting MALAT1 induces DNA damage and sensitize non-small cell lung cancer cells to cisplatin by repressing BRCA1.
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA which has been identified to be involved in alternative non-homologous end joining (A-NHEJ) pathways by binding with PARP1 and LIG3 in myeloma cells. This study aims to explore the roles of MALAT1 in DNA repair processes in non-small cell lung cancer (NSCLC).The interactions between MALAT1 and proteins were identified ... [more]
Cancer Chemother Pharmacol Dec. 01, 2019; 86(5);663-672 [Pubmed: 33030583]
Throughput
- Low Throughput
Curated By
- BioGRID