Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the "b"domain of C9.

Ninomiya H, Sims PJ

The erythrocyte membrane inhibitor of the human terminal complement proteins, surface antigen CD59, has previously been shown to enter into a detergent-resistant complex with either the membrane-bound complex of C5b-8 or C5b-9 (Meri, S., Morgan, B. P., Davies, A., Daniels, R. H., Olavesen, M. G., Waldmann, H. and Lachmann, P. J. (1990) Immunology 71, 1-9; Rollins, S. A., Zhao, J., ... [more]

J. Biol. Chem. Jul. 05, 1992; 267(19);13675-80 [Pubmed: 1377690]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CD59 C9
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID