NRCAM
Gene Ontology Biological Process
- angiogenesis [IEP]
- axon guidance [TAS]
- axonal fasciculation [NAS]
- axonogenesis [NAS]
- central nervous system development [NAS]
- clustering of voltage-gated sodium channels [IDA]
- neuron migration [NAS]
- positive regulation of neuron differentiation [NAS]
- regulation of axon extension [NAS]
- single organismal cell-cell adhesion [NAS]
- synapse assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PTPRB
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta.
Receptor protein tyrosine phosphatase beta (RPTPbeta) is expressed as soluble and receptor forms with common extracellular regions consisting of a carbonic anhydrase domain (C), a fibronectin type III repeat (F), and a unique region called S. We showed previously that a recombinant Fc fusion protein with the C domain (beta C) binds to contactin and supports neuronal adhesion and neurite ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID