MET
Gene Ontology Biological Process
- axon guidance [TAS]
- branching morphogenesis of an epithelial tube [IMP]
- cell proliferation [TAS]
- cell surface receptor signaling pathway [NAS]
- endothelial cell morphogenesis [IDA]
- negative regulation of hydrogen peroxide-mediated programmed cell death [IMP]
- peptidyl-tyrosine phosphorylation [NAS, TAS]
- positive chemotaxis [IDA]
- positive regulation of endothelial cell chemotaxis [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- semaphorin-plexin signaling pathway [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SOS1
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Ras protein signal transduction [TAS]
- apoptotic signaling pathway [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- leukocyte migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- positive regulation of Ras GTPase activity [EXP, TAS]
- positive regulation of Rho GTPase activity [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- signal transduction [NAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Signaling by HGF and KGF in corneal epithelial cells: Ras/MAP kinase and Jak-STAT pathways.
PURPOSE: To characterize the signaling pathways used by hepatocyte growth factor (HGF) and keratinocyte growth factor (KGF) in human corneal epithelial cells. METHODS: Cultures of SV40 large T antigen-transfected human corneal epithelial cells were treated with recombinant human HGF or KGF at 50 ng/ml to 100 ng/ml for 5 to 30 minutes and harvested for protein isolation. Immunoprecipitation was performed ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID