BAIT
SLC4A1
AE1, BND3, CD233, DI, EMPB3, EPB3, FR, RTA1A, SW, WD, WD1, WR
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
GO Process (7)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function- anion transmembrane transporter activity [TAS]
- anion:anion antiporter activity [IDA]
- ankyrin binding [IPI]
- bicarbonate transmembrane transporter activity [IDA]
- chloride transmembrane transporter activity [ISS]
- inorganic anion exchanger activity [IDA, TAS]
- protein anchor [TAS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- anion transmembrane transporter activity [TAS]
- anion:anion antiporter activity [IDA]
- ankyrin binding [IPI]
- bicarbonate transmembrane transporter activity [IDA]
- chloride transmembrane transporter activity [ISS]
- inorganic anion exchanger activity [IDA, TAS]
- protein anchor [TAS]
- protein binding [IPI]
- protein homodimerization activity [IPI]
Gene Ontology Cellular Component
Homo sapiens
PREY
CA2
CA-II, CAC, CAII, Car2, HEL-76
carbonic anhydrase II
GO Process (6)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Localization of the Cl-/HCO3- anion exchanger binding site to the amino-terminal region of carbonic anhydrase II.
Human carbonic anhydrase II (CAII) possesses a binding site for an acidic motif (D887ADD) within the carboxyl-terminal region (Ct) of the human erythrocyte chloride/bicarbonate anion exchanger, AE1. In this study, the amino acid sequence comprising this AE1 binding site was localized to the first 17 residues of CAII, which form a basic patch on the surface of the protein. Truncation ... [more]
Biochemistry Nov. 07, 2000; 39(44);13344-9 [Pubmed: 11063570]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CA2 SLC4A1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| SLC4A1 CA2 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| SLC4A1 CA2 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID