SYTL5
Gene Ontology Biological Process
Gene Ontology Molecular Function
RAB27A
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [ISO]
- blood coagulation [IMP]
- complement-dependent cytotoxicity [ISO]
- cytotoxic T cell degranulation [IMP]
- exocytosis [ISO]
- exosomal secretion [ISO]
- melanocyte differentiation [IMP]
- melanosome localization [IMP, ISO]
- melanosome transport [IMP]
- multivesicular body organization [ISO]
- multivesicular body sorting pathway [ISO]
- natural killer cell degranulation [IMP]
- pigment granule localization [IMP]
- pigment granule transport [IMP]
- pigmentation [IMP]
- positive regulation of constitutive secretory pathway [ISO]
- positive regulation of exocytosis [IBA, ISO]
- positive regulation of gene expression [ISO]
- positive regulation of phagocytosis [ISO]
- positive regulation of reactive oxygen species biosynthetic process [ISO]
- positive regulation of regulated secretory pathway [ISO]
- protein secretion [IBA]
- protein targeting [IMP]
- vesicle docking involved in exocytosis [IBA]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- Weibel-Palade body [ISO]
- apical plasma membrane [ISO]
- cell [IBA]
- dendrite [ISO]
- exocytic vesicle [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IBA, ISS]
- late endosome [ISO]
- lysosome [ISO]
- melanosome [IDA, ISO]
- multivesicular body membrane [ISO]
- photoreceptor outer segment [IDA]
- secretory granule [IMP, ISO]
- secretory granule membrane [ISO]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains.
Synaptotagmin-like proteins 1-4 (Slp1-4) are new members of the carboxyl-terminal-type (C-type) tandem C2 proteins and are classified as a subfamily distinct from the synaptotagmin and the Doc2 families, because the Slp family contains a unique homology domain at the amino terminus, referred to as the Slp homology domain (SHD). We previously showed that the SHD functions as a binding site ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID