BAIT
STAT4
SLEB11
signal transducer and activator of transcription 4
GO Process (1)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
IL12RB2
RP11-102M16.1
interleukin 12 receptor, beta 2
GO Process (4)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Direct interaction of STAT4 with the IL-12 receptor.
Signal transduction by interleukin-12 (IL-12) requires phosphorylation and activation of STAT4. Direct interaction of the SH2 domain of STAT4 with a phosphotyrosine residue in the IL-12 receptor has been proposed to be required for the subsequent STAT4 phosphorylation. The IL-12 receptor beta2 subunit contains three tyrosine residues in its cytoplasmic domain. To test the hypothesis that one of these tyrosines ... [more]
Arch. Biochem. Biophys. Aug. 01, 1999; 368(1);147-55 [Pubmed: 10415122]
Throughput
- Low Throughput
Curated By
- BioGRID