CAMK2D
Gene Ontology Biological Process
- cardiac muscle cell contraction [ISS]
- cellular response to calcium ion [TAS]
- cytokine-mediated signaling pathway [TAS]
- endoplasmic reticulum calcium ion homeostasis [ISS]
- interferon-gamma-mediated signaling pathway [TAS]
- negative regulation of sodium ion transmembrane transport [IDA]
- negative regulation of sodium ion transmembrane transporter activity [IDA]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of cardiac muscle hypertrophy [IMP]
- protein autophosphorylation [IDA]
- protein oligomerization [IDA]
- protein phosphorylation [IDA]
- regulation of cardiac muscle cell action potential [ISS]
- regulation of cardiac muscle cell action potential involved in regulation of contraction [IC]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC, TAS]
- regulation of cell communication by electrical coupling [ISS]
- regulation of cell communication by electrical coupling involved in cardiac conduction [IC]
- regulation of cell growth [NAS]
- regulation of cellular localization [IMP]
- regulation of generation of L-type calcium current [ISS]
- regulation of heart contraction [TAS]
- regulation of heart rate by cardiac conduction [IC]
- regulation of histone deacetylase activity [TAS]
- regulation of membrane depolarization [IDA]
- regulation of relaxation of cardiac muscle [IDA]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [ISS]
- regulation of ryanodine-sensitive calcium-release channel activity [TAS]
- regulation of the force of heart contraction [TAS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- relaxation of cardiac muscle [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RPS18
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- ribosome biogenesis [IBA]
- translation [IBA, IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The S18 ribosomal protein is a putative substrate for Ca2+/calmodulin-activated protein kinase II.
The delta-isoform of Ca(2+)/calmodulin-activated protein kinase II (CaMK II) is abundantly expressed in vascular smooth muscle, but relatively little is known about its regulation or its potential cellular substrates. There are few, if any, known substrates of CaMK II that are physiologically relevant in vascular smooth muscle cells. Studies presented earlier (Mishra-Gorur, K., Singer, H. A., and Castellot, J. J., ... [more]
Throughput
- Low Throughput
Additional Notes
- sequencing
Curated By
- BioGRID