BAIT
NMI
N-myc (and STAT) interactor
GO Process (4)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STAT5B
STAT5
signal transducer and activator of transcription 5B
GO Process (21)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- 2-oxoglutarate metabolic process [ISS]
- JAK-STAT cascade [TAS]
- JAK-STAT cascade involved in growth hormone signaling pathway [IDA, TAS]
- allantoin metabolic process [ISS]
- cellular response to epidermal growth factor stimulus [ISS]
- cellular response to growth factor stimulus [ISS]
- cellular response to hormone stimulus [IDA]
- citrate metabolic process [ISS]
- creatine metabolic process [ISS]
- creatinine metabolic process [ISS]
- fatty acid metabolic process [ISS]
- isoleucine metabolic process [ISS]
- oxaloacetate metabolic process [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- prolactin signaling pathway [ISS]
- regulation of multicellular organism growth [ISS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- response to estradiol [IDA]
- succinate metabolic process [ISS]
- taurine metabolic process [ISS]
- valine metabolic process [ISS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling.
Using the coiled-coil region of Stat5b as the bait in a yeast two-hybrid screen, we identified the association of Nmi, a protein of unknown function previously reported as an N-Myc interactor. We further show that Nmi interacts with all STATs except Stat2. We evaluated two cytokine systems, IL-2 and IFNgamma, and demonstrate that Nmi augments STAT-mediated transcription in response to ... [more]
Cell Jan. 08, 1999; 96(1);121-30 [Pubmed: 9989503]
Throughput
- Low Throughput
Curated By
- BioGRID