BAIT

EPS15L1

9830147J04Rik, AI593686, Eps15-rs, Eps15R
epidermal growth factor receptor pathway substrate 15-like 1
GO Process (0)
GO Function (1)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

NUMB

C14orf41, S171, c14_5527
numb homolog (Drosophila)
Alzheimer's Disease Project
Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.

Salcini AE, Confalonieri S, Doria M, Santolini E, Tassi E, Minenkova O, Cesareni G, Pelicci PG, Di Fiore PP

EH is a recently identified protein-protein interaction domain found in the signal transducers Eps15 and Eps15R and several other proteins of yeast nematode. We show that EH domains from Eps15 and Eps15R bind in vitro to peptides containing an asparagine-proline-phenylalanine (NPF) motif. Direct screening of expression libraries with EH domains yielded a number of putative EH interactors, all of which ... [more]

Genes Dev. Sep. 01, 1997; 11(17);2239-49 [Pubmed: 9303539]

Throughput

  • Low Throughput

Curated By

  • BioGRID