BAIT
EPS15
2410112D09Rik, RP23-414M10.3
epidermal growth factor receptor pathway substrate 15
GO Process (2)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NUMBL
CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23
numb homolog (Drosophila)-like
GO Process (6)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.
EH is a recently identified protein-protein interaction domain found in the signal transducers Eps15 and Eps15R and several other proteins of yeast nematode. We show that EH domains from Eps15 and Eps15R bind in vitro to peptides containing an asparagine-proline-phenylalanine (NPF) motif. Direct screening of expression libraries with EH domains yielded a number of putative EH interactors, all of which ... [more]
Genes Dev. Sep. 01, 1997; 11(17);2239-49 [Pubmed: 9303539]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| EPS15 NUMBL | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | Low | - | BioGRID | - |
Curated By
- BioGRID