Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Rabphilin-3A binds to a M(r) 115,000 polypeptide in a phosphatidylserine- and Ca(2+)-dependent manner.

Miyazaki M, Kaibuchi K, Shirataki H, Kohno H, Ueyama T, Nishikawa J, Takai Y

Rabphilin-3A is a putative target protein for Rab3A/Smg 25A, which is a member of the Ras-related small GTP-binding protein and implicated in neurotransmitter release from the synapse. Rabphilin-3A is composed of two functionally different domains: the N-terminal Rab3A-binding and the C-terminal phosphatidylserine- and Ca(2+)-binding domains. The C-terminal domain has two copies of an internal repeat that are homologous to the ... [more]

Brain Res. Mol. Brain Res. Jan. 01, 1995; 28(1);29-36 [Pubmed: 7707875]

Throughput

  • Low Throughput

Curated By

  • BioGRID