BAIT
EZR
CVIL, CVL, HEL-S-105, VIL2
ezrin
GO Process (7)
GO Function (4)
GO Component (18)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [IDA]
- actin filament [IDA]
- apical part of cell [IDA]
- basolateral plasma membrane [ISS]
- cell periphery [IDA]
- cortical cytoskeleton [TAS]
- cytosol [IDA, TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- extrinsic component of membrane [IDA]
- filopodium [IDA]
- focal adhesion [IDA]
- membrane [IDA]
- microvillus [IDA]
- nucleolus [IDA]
- plasma membrane [IDA]
- ruffle [IDA]
- vesicle [IDA]
Homo sapiens
PREY
SELP
CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL, RP1-86F14.2
selectin P (granule membrane protein 140kDa, antigen CD62)
GO Process (11)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell adhesion [TAS]
- defense response to Gram-negative bacterium [IC]
- leukocyte cell-cell adhesion [IDA]
- leukocyte migration [TAS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of platelet activation [ISS]
- regulation of integrin activation [IMP]
- response to lipopolysaccharide [IC]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells.
In response to the chemoattractants interleukin 8, C5a, N-formyl-methionyl-leucyl-phenylalanine, and interleukin 15, adhesion molecules P-selectin glycoprotein ligand 1 (PSGL-1), intercellular adhesion molecule 3 (ICAM-3), CD43, and CD44 are redistributed to a newly formed uropod in human neutrophils. The adhesion molecules PSGL-1 and ICAM-3 were found to colocalize with the cytoskeletal protein moesin in the uropod of stimulated neutrophils. Interaction of ... [more]
Blood Apr. 01, 2000; 95(7);2413-9 [Pubmed: 10733515]
Throughput
- Low Throughput
Curated By
- BioGRID