BAIT
STX1A
HPC-1, P35-1, STX1, SYN1A
syntaxin 1A (brain)
GO Process (11)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- cellular protein metabolic process [TAS]
- energy reserve metabolic process [TAS]
- glutamate secretion [TAS]
- intracellular protein transport [IBA]
- neurotransmitter secretion [TAS]
- regulation of insulin secretion [TAS]
- secretion by cell [IDA]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SYT1
P65, SVP65, SYT
synaptotagmin I
GO Process (10)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- detection of calcium ion [TAS]
- fast, calcium ion-dependent exocytosis of neurotransmitter [ISS]
- glutamate secretion [TAS]
- neurotransmitter secretion [TAS]
- positive regulation of synaptic transmission [ISS]
- protein homooligomerization [TAS]
- regulation of exocytosis [TAS]
- regulation of regulated secretory pathway [ISS]
- regulation of synaptic transmission, glutamatergic [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin-sculpted acetylcholine transport vesicle membrane [TAS]
- clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane [TAS]
- clathrin-sculpted glutamate transport vesicle membrane [TAS]
- clathrin-sculpted monoamine transport vesicle membrane [TAS]
- endocytic vesicle membrane [TAS]
- neuron projection [ISS]
- plasma membrane [TAS]
- synaptic vesicle [TAS]
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Functional and biochemical analysis of the C2 domains of synaptotagmin IV.
Synaptotagmins (Syts) are a family of vesicle proteins that have been implicated in both regulated neurosecretion and general membrane trafficking. Calcium-dependent interactions mediated through their C2 domains are proposed to contribute to the mechanism by which Syts trigger calcium-dependent neurotransmitter release. Syt IV is a novel member of the Syt family that is induced by cell depolarization and has a ... [more]
Mol. Biol. Cell Jul. 01, 1999; 10(7);2285-95 [Pubmed: 10397765]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SYT1 STX1A | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| SYT1 STX1A | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID