Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Functional and biochemical analysis of the C2 domains of synaptotagmin IV.

Thomas DM, Ferguson GD, Herschman HR, Elferink LA

Synaptotagmins (Syts) are a family of vesicle proteins that have been implicated in both regulated neurosecretion and general membrane trafficking. Calcium-dependent interactions mediated through their C2 domains are proposed to contribute to the mechanism by which Syts trigger calcium-dependent neurotransmitter release. Syt IV is a novel member of the Syt family that is induced by cell depolarization and has a ... [more]

Mol. Biol. Cell Jul. 01, 1999; 10(7);2285-95 [Pubmed: 10397765]

Throughput

  • Low Throughput

Curated By

  • BioGRID