BAIT
STX1B
Stx1b2, Stx2
syntaxin 1B
GO Process (11)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- intracellular protein transport [IBA]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of neurotransmitter secretion [ISS]
- protein transport [IMP]
- regulation of exocytosis [IMP]
- regulation of gene expression [ISS]
- regulation of synaptic vesicle priming [ISS]
- synaptic vesicle docking [ISS]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
STXBP1
ANC18HA, Munc18-1, NSEC1A, Sec1, Unc18-1, n-sec1, nSec1, rbSec1, rbSec1A, rbSec1B
syntaxin binding protein 1
GO Process (16)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- axon target recognition [ISO]
- exocytosis [ISO]
- long term synaptic depression [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of synaptic transmission, GABAergic [ISO]
- neuromuscular synaptic transmission [ISO]
- neurotransmitter secretion [ISO]
- platelet aggregation [ISO]
- platelet degranulation [ISO]
- positive regulation of calcium ion-dependent exocytosis [ISO]
- positive regulation of exocytosis [IMP]
- protein localization to plasma membrane [ISO]
- protein stabilization [IDA]
- regulation of synaptic vesicle priming [IMP]
- synaptic vesicle maturation [ISO]
- vesicle docking involved in exocytosis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
n-Sec1: a neural-specific syntaxin-binding protein.
We have identified n-Sec1, a rat brain homolog of the yeast Sec1p protein that participates in the constitutive secretory pathway between the Golgi apparatus and the plasma membrane. The rat brain cDNA is predicted to encode a 68-kDa protein with 65% amino acid identity to Drosophila rop, 59% identity to Caenorhabditis elegans unc-18, and 27% identity to Saccharomyces cerevisiae Sec1p. ... [more]
Proc. Natl. Acad. Sci. U.S.A. Feb. 15, 1994; 91(4);1445-9 [Pubmed: 8108429]
Throughput
- Low Throughput
Curated By
- BioGRID