Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth.

Kinnunen T, Kaksonen M, Saarinen J, Kalkkinen N, Peng HB, Rauvala H

N-syndecan (syndecan-3) was previously isolated as a cell surface receptor for heparin-binding growth-associated molecule (HB-GAM) and suggested to mediate the neurite growth-promoting signal from cell matrix-bound HB-GAM to the cytoskeleton of neurites. However, it is unclear whether N-syndecan would possess independent signaling capacity in neurite growth or in related cell differentiation phenomena. In the present study, we have transfected N18 ... [more]

J. Biol. Chem. Apr. 24, 1998; 273(17);10702-8 [Pubmed: 9553134]

Throughput

  • Low Throughput

Curated By

  • BioGRID