CTNNA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CDH3
Gene Ontology Biological Process
- adherens junction organization [TAS]
- canonical Wnt signaling pathway [IMP]
- cell adhesion [TAS]
- cell junction assembly [TAS]
- cell-cell junction organization [TAS]
- hair cycle process [IMP]
- keratinization [IMP]
- negative regulation of catagen [IMP]
- negative regulation of transforming growth factor beta2 production [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of insulin-like growth factor receptor signaling pathway [IMP]
- positive regulation of keratinocyte proliferation [IMP]
- positive regulation of melanin biosynthetic process [IMP]
- positive regulation of melanosome transport [IMP]
- positive regulation of monophenol monooxygenase activity [IMP]
- regulation of hair cycle by canonical Wnt signaling pathway [IMP]
- retina homeostasis [IMP]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The fate of E- and P-cadherin during the early stages of apoptosis.
Caspases are responsible for the proteolysis of many cytoskeletal proteins in apoptotic cells. It has been demonstrated here that during cisplatin-induced apoptosis of human embryo retinoblasts both E- and P-cadherin were degraded by caspases, giving initially major polypeptide products of apparent molecular weights 48 K and 104 K respectively. This proteolysis occurred over a similar time-scale to the observed degradation ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDH3 CTNNA1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| CDH3 CTNNA1 | Co-purification Co-purification An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps. | Low | - | BioGRID | - |
Curated By
- BioGRID