Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Intracellular interaction of EBV/C3d receptor (CR2) with p68, a calcium-binding protein present in normal but not in transformed B lymphocytes.

Barel M, Gauffre A, Lyamani F, Fiandino A, Hermann J, Frade R

To analyze direct intracellular interactions of CR2 in normal human B lymphocytes, we used polyclonal anti-Id anti-CR2 antibodies (Ab2) prepared against the highly purified CR2 molecule (gp140) as original immunogen. We previously demonstrated that this Ab2 contained specificities that mimicked extracellular and intracellular domains of CR2 and was helpful for identifying CR2-specific ligands. Indeed, some Ab2 specificities recognized human C3d ... [more]

J. Immunol. Aug. 15, 1991; 147(4);1286-91 [Pubmed: 1831222]

Throughput

  • Low Throughput

Curated By

  • BioGRID