Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Effects of calcium-binding proteins (S-100a(o), S-100a, S-100b) on desmin assembly in vitro.

Garbuglia M, Verzini M, Giambanco I, Spreca A, Donato R

S-100a(o), the alpha alpha isoform of a subfamily of Ca(2+)-binding proteins of the EF-hand type expressed in cardiac and skeletal muscle cells, is reported to inhibit the assembly of the intermediate filament subunit desmin and to stimulate the disassembly of desmin intermediate filaments in the presence of micromolar levels of free Ca(2+). These effects are dose-dependent with respect to the ... [more]

FASEB J. Feb. 01, 1996; 10(2);317-24 [Pubmed: 8641565]

Throughput

  • Low Throughput

Curated By

  • BioGRID