SEMA4D
Gene Ontology Biological Process
- axon guidance [TAS]
- cell adhesion [TAS]
- immune response [TAS]
- leukocyte aggregation [IMP]
- negative regulation of alkaline phosphatase activity [IMP]
- negative regulation of apoptotic process [TAS]
- negative regulation of cell adhesion [IDA]
- negative regulation of osteoblast differentiation [ISS]
- negative regulation of peptidyl-tyrosine phosphorylation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- ossification involved in bone maturation [IMP]
- positive regulation of Rho GTPase activity [IMP, ISS]
- positive regulation of cell migration [IDA, ISS]
- positive regulation of collateral sprouting [IMP]
- positive regulation of peptidyl-tyrosine phosphorylation [ISS]
- positive regulation of phosphatidylinositol 3-kinase signaling [IMP]
- positive regulation of protein phosphorylation [IDA]
- regulation of cell projection organization [IMP]
- regulation of cell shape [IMP]
- regulation of dendrite morphogenesis [IMP]
- semaphorin-plexin signaling pathway [IDA, IMP]
- semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SEMA4D
Gene Ontology Biological Process
- axon guidance [TAS]
- cell adhesion [TAS]
- immune response [TAS]
- leukocyte aggregation [IMP]
- negative regulation of alkaline phosphatase activity [IMP]
- negative regulation of apoptotic process [TAS]
- negative regulation of cell adhesion [IDA]
- negative regulation of osteoblast differentiation [ISS]
- negative regulation of peptidyl-tyrosine phosphorylation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- ossification involved in bone maturation [IMP]
- positive regulation of Rho GTPase activity [IMP, ISS]
- positive regulation of cell migration [IDA, ISS]
- positive regulation of collateral sprouting [IMP]
- positive regulation of peptidyl-tyrosine phosphorylation [ISS]
- positive regulation of phosphatidylinositol 3-kinase signaling [IMP]
- positive regulation of protein phosphorylation [IDA]
- regulation of cell projection organization [IMP]
- regulation of cell shape [IMP]
- regulation of dendrite morphogenesis [IMP]
- semaphorin-plexin signaling pathway [IDA, IMP]
- semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation.
Lymphocyte activation induces or increases the expression of several surface structures, some of which are directly involved in cell growth such as receptors for IL-2 or transferrin. In order to identify new structures characteristic of activated lymphocytes, we developed a series of mAb against functionally defined human T cell clones. In the present study we report the isolation of a ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID