Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Mammalian CAP interacts with CAP, CAP2, and actin.

Hubberstey A, Yu G, Loewith R, Lakusta C, Young D

We previously identified human CAP, a homolog of the yeast adenylyl cyclase-associated protein. Previous studies suggest that the N-terminal and C-terminal domains of CAP have distinct functions. We have explored the interactions of human CAP with various proteins. First, by performing yeast two-hybrid screens, we have identified peptides from several proteins that interact with the C-terminal and/or the N-terminal domains ... [more]

J. Cell. Biochem. Jun. 01, 1996; 61(3);459-66 [Pubmed: 8761950]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
CAP1 BAG6	Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro.	Hubberstey A (1996)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

CAP1

Gene Ontology Biological Process

Gene Ontology Cellular Component

BAG6

Gene Ontology Biological Process

Gene Ontology Molecular Function

Hsp70 protein binding [IPI]polyubiquitin binding [IDA]proteasome binding [IDA]protein binding [IPI]ribosome binding [ISO]ubiquitin protein ligase binding [ISO]