BAIT

CG10139

Dmel\CG10139, Dmel_CG10139

CG10139 gene product from transcript CG10139-RB

GO Process (0)

GO Function (0)

GO Component (0)

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

PREY

FD68A

CG11799, DmLD16137, DmMNF, Dmel\CG11799, FoxK, MNF, fork head transcription factor long isoform, fork head transcription factor short isoform, Dmel_CG11799

forkhead domain 68A

GO Process (6)

GO Function (6)

GO Component (2)

Gene Ontology Biological Process

midgut development [IMP]

negative regulation of transcription from RNA polymerase II promoter [IBA]

pattern specification process [IBA]

regulation of sequence-specific DNA binding transcription factor activity [IBA]

tissue development [IBA]

visceral mesoderm-endoderm interaction involved in midgut development [IMP]

Gene Ontology Molecular Function

DNA binding, bending [IBA]
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IBA]
double-stranded DNA binding [IBA]
magnesium ion binding [IBA]
sequence-specific DNA binding transcription factor activity [IDA, ISS]
transcription factor binding [IBA]

Gene Ontology Cellular Component

nucleus [IDA, ISS]

transcription factor complex [IBA]

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A protein interaction map of Drosophila melanogaster.

Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, Li Y, Hao YL, Ooi CE, Godwin B, Vitols E, Vijayadamodar G, Pochart P, Machineni H, Welsh M, Kong Y, Zerhusen B, Malcolm R, Varrone Z, Collis A, Minto M, Burgess S, McDaniel L, Stimpson E, Spriggs F, Williams J, Neurath K, Ioime N, Agee M, Voss E, Furtak K, Renzulli R, Aanensen N, Carrolla S, Bickelhaupt E, Lazovatsky Y, DaSilva A, Zhong J, Stanyon CA, Finley RL, White KP, Braverman M, Jarvie T, Gold S, Leach M, Knight J, Shimkets RA, McKenna MP, Chant J, Rothberg JM

Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]

Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]

Throughput

High Throughput

Curated By

BioGRID

Interaction Summary